UV Spectrophotometric method has been developed for simultaneous estimation of amlodipine besylate (AB) and candesartan cilexetil (CC) in bulk drug and in laboratory mixture. This method utilizes methanol as a solvent and λ max of amlodipine besylate and candesartan cilexetil selected for analysis was found to be 238 nm and 255 nm respectively. Linearity was observed in the concentration range of 5-25 μg/ml and (r2 = 0.999) of both drugs. The accuracy and precision were determined and found to comply with ICH guidelines. This method showed good reproducibility and recovery with % RSD in the desired range. The proposed methods can be successfully applied for the routine analysis of both the drugs in Synthetic mixture. This method was simple, rapid, accurate and sensitive.
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